Lithium and lamictal in children: An effective combination

Lithium and lamictal can be used effectively in combination in children who have irritability and mood dysregulation that does not respond to a single mood stabilizer. Also for those rapid cyclers who don't respond to other medications. Response can be seen with lower doses of each. One can give all the Lithium at night to prevent headaches. If needed they can both be titrated to a fully therapeutic blood using blood levels as a guide.